Pesticides, when not judiciously used, may disrupt natural biological pest control mechanisms. More vigorous pest attacks may result, along with heavier chemical use, and increased health exposures. Pesticides, as well as fertilizers, can infiltrate water sources – contaminating drinking water and animal species, e.g. fish, upon which humans rely for nutrition. Such contamination can lead to a range of secondary public health impacts


http://www.who.int/heli/risks/toxics/chemicals/en/index.html